Jim West is a guns-a-blazing former Civil War hero. Artemus Gordon is an inventive U.S. Marshal who excels in disguise. When the United States is threatened by psychotic Confederate Arliss Loveless, President Ulysses Grant teams the duo up to bring him to justice. On a hazard-packed train journey from Washington D.C. to Utah, West and Gordon must combine their skills to best Loveless and his diabolical machines.